The concomitant use of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors might result in a rise in methadone plasma concentrations, which could cause probably deadly respiratory melancholy. Moreover, discontinuation of concomitantly used cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers might also cause a rise in methadone plas… Read More